KMID : 0357920100440020199
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Korean Journal of Pathology 2010 Volume.44 No. 2 p.199 ~ p.203
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A Case of Paraduodenal Pancreatitis and Immunohistochemical Analysis
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Kwon Mi-Jung
Nam Eun-Sook Cho Seong-Jin Shin Hyung-Sik Kim Joo-Seop Kim Doo-Jin
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Abstract
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Paraduodenal pancreatitis (PP) is a rare, distinct form of chronic pancreatitis, and it is related to alcohol abuse in middle-aged men. A 36-year-old man with a history of chronic recurrent pancreatitis for 4 years and alcohol abuse for 15 years presented with abdominal pain. Computed tomography revealed a multilocular cystic mass 3.2¡¿3¡¿3 cm in size and it was located within the muscular layer of the duodenal wall. The cysts were lined by a single layer of eosinophilic cuboidal epithelial cells that stained positively for mucin (MUC)1, MUC6, cytokeratin (CK)7 and CK19 and they stained negatively for MUC2, MUC5AC and CK5/6. Mild, chronic inflammatory reaction around the cystic wall, Brunner¡¯s gland hyperplasia and several clusters of heterotopic pancreatic tissue were noted. We report here on a case of PP and we demonstrated that the pancreatitis was of pancreatic ductal cell origin according to the MUC and CK expression patterns we observed on the immunohistochemical analysis.
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KEYWORD
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Pancreatitis, chronic, Pancreatic ducts, Cysts
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