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KMID : 0357920100440020199
Korean Journal of Pathology
2010 Volume.44 No. 2 p.199 ~ p.203
A Case of Paraduodenal Pancreatitis and Immunohistochemical Analysis
Kwon Mi-Jung

Nam Eun-Sook
Cho Seong-Jin
Shin Hyung-Sik
Kim Joo-Seop
Kim Doo-Jin
Abstract
Paraduodenal pancreatitis (PP) is a rare, distinct form of chronic pancreatitis, and it is related to alcohol abuse in middle-aged men. A 36-year-old man with a history of chronic recurrent pancreatitis for 4 years and alcohol abuse for 15 years presented with abdominal pain. Computed tomography revealed a multilocular cystic mass 3.2¡¿3¡¿3 cm in size and it was located within the muscular layer of the duodenal wall. The cysts were lined by a single layer of eosinophilic cuboidal epithelial cells that stained positively for mucin (MUC)1, MUC6, cytokeratin (CK)7 and CK19 and they stained negatively for MUC2, MUC5AC and CK5/6. Mild, chronic inflammatory reaction around the cystic wall, Brunner¡¯s gland hyperplasia and several clusters of heterotopic pancreatic tissue were noted. We report here on a case of PP and we demonstrated that the pancreatitis was of pancreatic ductal cell origin according to the MUC and CK expression patterns we observed on the immunohistochemical analysis.
KEYWORD
Pancreatitis, chronic, Pancreatic ducts, Cysts
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